1105601 UiO Life Sciences user equipment. K935.11 Super resolution microscope

Statsbygg is building the new Life Science Building (LVB) for the University of Oslo and Oslo University Hospital on behalf of the Ministry of Education and Research and South-East Health as with the contracting authority. The building shall be the workplace for approx. 1,600 employees and 1,600 students. Start up for the excavation and ground work was the second quarter of 2019 and the planned completion is at the end of 2026. Various professional environments shall work multi-disciplinary here to develop new solutions for major challenges within health and sustainability with access to the best and most modern equipment required to carry out world class research, teaching and innovation. Statsbygg requests tenders for an inverted super-resolution microscope with SMLM, SIM and TIRF modality. More detailed information: The super resolution microscope will be placed inside a BSL3 lab and used for the study of pathogenic bacteria and viruses and their interactions with host cells like macrophages or cell cultures. A Super-resolution fluorescent-microscope (SRM) with SIM, SMLM and TIRF that enables high resolution fluorescence microscopy of living microbes (bacteria and fugi), host pathogen-interactions (macrophages and infected cells), and organoids/tissues at single cell level, to be able to study molecular cell localisation and molecular interactions. Shall be equipped with stage incubation chamber with control of CO2 and temperature, and motorised stage with holders for slides and multiwell plates. The system shall be delivered with a computer with a suitable software package for controlling the microscope and analysis and post-processing of images, and in addition a second computer placed outside BSL3 for analysis and post-processing of images in a more convenient location.